Can I Use Estriol Oil Every Day?

April 30, 2024

Can I Use Estriol Oil Every Day?

Are you thinking about taking estriol oil as hormone therapy and wondering if you can take it every day? This is a good question many people have, regardless of the reason for considering it. Estriol is a weak estrogen and is commonly used in menopausal hormone therapy. As a natural hormone, it's safe to take every day, and here's why.

Understanding Estriol

Estrogen is a sex hormone primarily produced in the ovaries during a woman's reproductive years and by the placenta during pregnancy. In men and postmenopausal women, smaller amounts of estrogen are made in the adrenal glands and by fat tissues throughout the body. Additionally, the testes in men produce a modest amount of estrogen. Estrogen is vital for both men and women in that it regulates fertility. It is essential for cardiovascular health and bone density.

Estrogen comes in three distinct forms, each with a specific purpose.

Estrone (E1):  It is the most prominent form of estrogen after a woman goes through menopause. The production comes from the adrenal glands and fatty tissues, and some convert to the more potent estradiol.

Estradiol (E2): It is the prevalent and potent form of estrogen during a woman's reproductive years. It's crucial for conception and maintaining a healthy pregnancy. As women age, levels taper off, causing hormonal imbalance, which leads to menopause.

Estriol (E3): As mentioned, it is a weak form of estrogen. After conception, estriol levels increase due to pregnancy and help prepare the body for birth. It also helps develop the fetus and prepare the body for breastfeeding. 

The Benefits of Estriol Oil

While estriol levels increase during pregnancy, when you have low estrogen, either due to menopause or a health condition, estriol replacement therapy can help alleviate symptoms. Menopausal women can experience a myriad of symptoms from low estrogen. By far, the most common are vaginal atrophy and hot flashes.

Alleviates Vaginal Dryness

Low estrogen can result in the thinning and tightening of your vaginal tissues. Estrogen infuses your steroid hormones in the vaginal skin with elasticity and moistness. This infusion helps make intercourse more pleasurable and allows the opening up of penetration.

Postmenopausal women, in particular, suffer from dry skin conditions, causing sexual activity to be excruciating. Also, the shape of the vagina can change, making sex more painful. Estriol oil can be applied directly to the vaginal tissues or taken orally. Research shows that estriol improves vaginal moisture and can make sexual intercourse pleasurable again. 

Improves Hot Flashes

By far, the most common symptom of menopause and low estriol levels is hot flashes. Hot flashes are intense heat that sweeps over your body suddenly and without provocation. They can also come with a surge in nausea and deep unrest. In an instant, you're covered with intense heat and then droplets of sweat. Some women report removing clothes immediately to alleviate the heat and feeling cold a few minutes later. You can have multiple hot flashes every day for years.

Estriol cream or oil improves estrogen levels, enhancing body temperature regulation. Estrogen receptors in the body soak up the estrogen cream to help alleviate hot flashes. 

Supports Bone Health

Another huge benefit of estriol oil supplementation is improving bone mineral density. Estrogen helps build strong bones and prevents osteoporosis, a breakdown of bone mass. Due to plummeting estrogen levels, postmenopausal women, in particular, are at an increased risk for osteoporosis.

In particular, estradiol, the most potent estrogen, is no longer produced. Instead, estrone is common, and some can be converted to estradiol, but not enough to prevent bone disease, if a woman is at risk of developing it.

Prevents Weight Gain

One pesky symptom of low estrogen is weight gain, especially around the middle. Low estrogen increases belly fat and muscle weakness, resulting in a belly pooch. Gaining weight around the middle has overall health consequences but also results in a feeling of unattractiveness. Boosting estriol levels decreases the fat around your stomach but also lifts your mood and positive feelings about your body.

Daily Use and Dosage 


Consult your healthcare professional to measure your estriol levels and determine the correct amount for you. Still, we'll touch on some recommended dosages.

Estriol oil from BIOLabs Pro are completely natural and infused with MCT oil, estriol, and vitamin E. One bottle contains 1,600 drops, each containing .5 mg of bioidentical estriol oil. The recommended daily dose is 5-10 drops. The oils are designed to be applied topically to the skin but can also be taken orally.

Women can supplement with estriol oil vaginally. You insert a low-dose vaginal oil inside your vagina, and estrogen receptors soak up the medicine. Supplementation can be inserted daily, like estriol oil applied to the skin. For the right amount for your needs, consult your doctor.

Risks and Considerations

Safety concerns around estrogen hormone replacement aren't something new. Historically, hormone therapy to alleviate menopause has been prescribed for decades. Yet it wasn't until a landmark study by the Women's Health Initiative (WHI) that hormone therapy was actively discouraged by the traditional medical community. Conclusions from the study seemed to show that hormone therapy had adverse effects, such as an increased risk of breast cancer, endometrial hyperplasia, and stroke.

Further review of the study at a later date showed that the increased risk of developing breast cancer and other adverse effects was only significant for women 10+ years post-menopause. 

For women not in this age range, the benefits of estrogen hormone replacement therapy outweigh the risks. However, it's essential to call your doctor if you have concerns. Lab testing by your health care professional can determine your estrogen levels and your specific menopausal stage.

Final Thoughts

The daily use of estriol oil is considered safe and effective. Bioidentical estriol oil is available over-the-counter, without a prescription, and made up of entirely natural ingredients. It helps with treating symptoms of hot flashes, vaginal atrophy, and weak bones. While completely safe, consulting with your doctor for individual consideration is essential.